Selected Tool: PPI DETAILS

Interaction Details SWI6 (YLR182W)

This page summarises the physical and genetic interactions known for the selected gene/protein. These interaction data are derived from BIOGRID and taken from SGD. Interactions with genes not in the homozygous screen data (essential or not available) are indicated.

Standard_gene_name SWI6 / Feature_Name YLR182W / Alias transcriptional regulator SWI6, SDS11, PSL8
Description Transcription cofactor; forms complexes with Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; also binds Stb1p to regulate transcription at START; cell wall stress induces phosphorylatio
Feature_Type ORF / Feature_qualifier Verified / Parent_feature_name chromosome 12
Deletant Not Essential / SGD link S000004172

Physical Interaction 93Genetic Interaction 490
Affinity Capture-MS = 22
Affinity Capture-RNA = 2
Affinity Capture-Western = 36
Biochemical Activity = 9
Co-purification = 1
PCA = 6
Protein-peptide = 1
Reconstituted Complex = 9
Two-hybrid = 7
Dosage Growth Defect = 4
Dosage Rescue = 19
Negative Genetic = 210
Phenotypic Enhancement = 11
Phenotypic Suppression = 16
Positive Genetic = 97
Synthetic Growth Defect = 69
Synthetic Lethality = 54
Synthetic Rescue = 10

SWI6 (YLR182W) displays 93 Physical Interaction(s) as listed below

Show/Hide +/- Physical Interaction(s)
1) Feature_Name YGL256W ADH4
Experiment_Type PCA
Citation Tarassov K, et al. (2008) An in vivo map of the yeast protein interactome. Science 320(5882):1465-70
2) Feature_Name YKL092C BUD2
Experiment_Type Affinity Capture-MS
Citation Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43
3) Feature_Name YFR028C CDC14 (Essential, not in YDL homozygous screen data)
Experiment_Type Biochemical Activity
Citation Geymonat M, et al. (2004) Clb6/Cdc28 and Cdc14 regulate phosphorylation status and cellular localization of Swi6. Mol Cell Biol 24(6):2277-85
4) Feature_Name YBR160W CDC28 (Essential, not in YDL homozygous screen data)
Experiment_Type Biochemical Activity
Citation Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
5) Feature_Name YBR160W CDC28 (Essential, not in YDL homozygous screen data)
Experiment_Type PCA
Citation Manderson EN, et al. (2008) A Novel Genetic Screen Implicates Elm1 in the Inactivation of the Yeast Transcription Factor SBF. PLoS One 3(1):e1500
6) Feature_Name YBR160W CDC28 (Essential, not in YDL homozygous screen data)
Experiment_Type Biochemical Activity
Citation Koivomagi M, et al. (2011) Dynamics of Cdk1 Substrate Specificity during the Cell Cycle. Mol Cell 42(5):610-23
7) Feature_Name YBR160W CDC28 (Essential, not in YDL homozygous screen data)
Experiment_Type PCA
Citation Ear PH, et al. (2013) Dissection of Cdk1-cyclin complexes in vivo. Proc Natl Acad Sci U S A 110(39):15716-21
8) Feature_Name YBR160W CDC28 (Essential, not in YDL homozygous screen data)
Experiment_Type Biochemical Activity
Citation Geymonat M, et al. (2004) Clb6/Cdc28 and Cdc14 regulate phosphorylation status and cellular localization of Swi6. Mol Cell Biol 24(6):2277-85
9) Feature_Name YAL040C CLN3
Experiment_Type Affinity Capture-Western
Citation Wang H, et al. (2009) Recruitment of Cln3 cyclin to promoters controls cell cycle entry via histone deacetylase and other targets. PLoS Biol 7(9):e1000189
10) Feature_Name YHR116W COX23
Experiment_Type PCA
Citation Tarassov K, et al. (2008) An in vivo map of the yeast protein interactome. Science 320(5882):1465-70
11) Feature_Name YGR218W CRM1 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-MS
Citation Kirli K, et al. (2015) A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife 4()
12) Feature_Name YJR017C ESS1 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-Western
Citation Atencio D, et al. (2014) The Yeast Ess1 Prolyl Isomerase Controls Swi6 and Whi5 Nuclear Localization. G3 (Bethesda) ()
13) Feature_Name YJR017C ESS1 (Essential, not in YDL homozygous screen data)
Experiment_Type Protein-peptide
Citation Atencio D, et al. (2014) The Yeast Ess1 Prolyl Isomerase Controls Swi6 and Whi5 Nuclear Localization. G3 (Bethesda) ()
14) Feature_Name YBR010W HHT1
Experiment_Type Affinity Capture-MS
Citation Gilmore JM, et al. (2012) Characterization of a highly conserved histone related protein, Ydl156w, and its functional associations using quantitative proteomic analyses. Mol Cell Proteomics 11(4):M111.011544
15) Feature_Name YNL031C HHT2
Experiment_Type Affinity Capture-MS
Citation Gilmore JM, et al. (2012) Characterization of a highly conserved histone related protein, Ydl156w, and its functional associations using quantitative proteomic analyses. Mol Cell Proteomics 11(4):M111.011544
16) Feature_Name YBR034C HMT1
Experiment_Type Affinity Capture-MS
Citation Jackson CA, et al. (2012) Proteomic analysis of interactors for yeast protein arginine methyltransferase Hmt1 reveals novel substrate and insights into additional biological roles. Proteomics 12(22):3304-14
17) Feature_Name YPL204W HRR25 (Essential, not in YDL homozygous screen data)
Experiment_Type Biochemical Activity
Citation Ho U, et al. (1997) Role of the casein kinase I isoform, Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 94(2):581-6
18) Feature_Name YPL204W HRR25 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-Western
Citation Ho U, et al. (1997) Role of the casein kinase I isoform, Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 94(2):581-6
19) Feature_Name YPL125W KAP120
Experiment_Type Affinity Capture-Western
Citation Kim KY, et al. (2010) Yeast Mpk1 cell wall integrity mitogen-activated protein kinase regulates nucleocytoplasmic shuttling of the Swi6 transcriptional regulator. Mol Biol Cell 21(9):1609-19
20) Feature_Name YLR096W KIN2
Experiment_Type Affinity Capture-MS
Citation Breitkreutz A, et al. (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328(5981):1043-6
21) Feature_Name YDL056W MBP1
Experiment_Type Affinity Capture-Western
Citation Ear PH and Michnick SW (2009) A general life-death selection strategy for dissecting protein functions. Nat Methods 6(11):813-6
22) Feature_Name YDL056W MBP1
Experiment_Type Reconstituted Complex
Citation Ear PH and Michnick SW (2009) A general life-death selection strategy for dissecting protein functions. Nat Methods 6(11):813-6
23) Feature_Name YDL056W MBP1
Experiment_Type Affinity Capture-MS
Citation Gavin AC, et al. (2002) Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415(6868):141-7
24) Feature_Name YDL056W MBP1
Experiment_Type Two-hybrid
Citation Bouquin N, et al. (1999) Association of the cell cycle transcription factor Mbp1 with the Skn7 response regulator in budding yeast. Mol Biol Cell 10(10):3389-400
25) Feature_Name YDL056W MBP1
Experiment_Type Affinity Capture-Western
Citation Siegmund RF and Nasmyth KA (1996) The Saccharomyces cerevisiae Start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6. Mol Cell Biol 16(6):2647-55
26) Feature_Name YDL056W MBP1
Experiment_Type Affinity Capture-MS
Citation Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43
27) Feature_Name YDL056W MBP1
Experiment_Type PCA
Citation Ear PH and Michnick SW (2009) A general life-death selection strategy for dissecting protein functions. Nat Methods 6(11):813-6
28) Feature_Name YDL056W MBP1
Experiment_Type Affinity Capture-Western
Citation Travesa A, et al. (2013) Repression of G1/S transcription is mediated via interaction of the GTB motifs of Nrm1 and Whi5 with Swi6. Mol Cell Biol 33(8):1476-86
29) Feature_Name YDL056W MBP1
Experiment_Type Affinity Capture-Western
Citation Harris MR, et al. (2013) Binding specificity of the G1/S transcriptional regulators in budding yeast. PLoS One 8(4):e61059
30) Feature_Name YDL056W MBP1
Experiment_Type Affinity Capture-Western
Citation Harris MR, et al. (2013) Binding specificity of the G1/S transcriptional regulators in budding yeast. PLoS One 8(4):e61059
31) Feature_Name YOR066W MSA1
Experiment_Type Affinity Capture-MS
Citation Ashe M, et al. (2008) The SBF- and MBF-associated Protein Msa1 Is Required for Proper Timing of G1-specific Transcription in Saccharomyces cerevisiae. J Biol Chem 283(10):6040-9
32) Feature_Name YKR077W MSA2
Experiment_Type Affinity Capture-MS
Citation Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43
33) Feature_Name YDR335W MSN5
Experiment_Type Two-hybrid
Citation Queralt E and Igual JC (2003) Cell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling. Mol Cell Biol 23(9):3126-40
34) Feature_Name YGL122C NAB2 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-RNA
Citation Batisse J, et al. (2009) Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. J Biol Chem 284(50):34911-7
35) Feature_Name YNR009W NRM1
Experiment_Type Affinity Capture-MS
Citation de Bruin RA, et al. (2006) Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell 23(4):483-96
36) Feature_Name YNR009W NRM1
Experiment_Type Affinity Capture-Western
Citation Harris MR, et al. (2013) Binding specificity of the G1/S transcriptional regulators in budding yeast. PLoS One 8(4):e61059
37) Feature_Name YNR009W NRM1
Experiment_Type Affinity Capture-Western
Citation Travesa A, et al. (2013) Repression of G1/S transcription is mediated via interaction of the GTB motifs of Nrm1 and Whi5 with Swi6. Mol Cell Biol 33(8):1476-86
38) Feature_Name YDR150W NUM1
Experiment_Type Two-hybrid
Citation Wang Y, et al. (2012) Coiled-coil networking shapes cell molecular machinery. Mol Biol Cell 23(19):3911-22
39) Feature_Name YDR150W NUM1
Experiment_Type Two-hybrid
Citation Wang Y, et al. (2012) Coiled-coil networking shapes cell molecular machinery. Mol Biol Cell 23(19):3911-22
40) Feature_Name YNL261W ORC5 (Essential, not in YDL homozygous screen data)
Experiment_Type Two-hybrid
Citation Matsuda K, et al. (2007) Yeast two-hybrid analysis of the origin recognition complex of Saccharomyces cerevisiae: interaction between subunits and identification of binding proteins. FEMS Yeast Res 7(8):1263-9
41) Feature_Name YML069W POB3 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-Western
Citation Takahata S, et al. (2009) The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters. EMBO J 28(21):3378-89
42) Feature_Name YML069W POB3 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-Western
Citation Takahata S, et al. (2009) FACT and Asf1 regulate nucleosome dynamics and coactivator binding at the HO promoter. Mol Cell 34(4):405-15
43) Feature_Name YLL036C PRP19 (Essential, not in YDL homozygous screen data)
Experiment_Type Co-purification
Citation Stevens SW, et al. (2002) Composition and functional characterization of the yeast spliceosomal penta-snRNP. Mol Cell 9(1):31-44
44) Feature_Name YPL153C RAD53 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-MS
Citation Smolka MB, et al. (2006) An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. J Cell Biol 175(5):743-53
45) Feature_Name YPL153C RAD53 (Essential, not in YDL homozygous screen data)
Experiment_Type Biochemical Activity
Citation Sidorova JM and Breeden LL (2003) Rad53 checkpoint kinase phosphorylation site preference identified in the Swi6 protein of Saccharomyces cerevisiae. Mol Cell Biol 23(10):3405-16
46) Feature_Name YPL153C RAD53 (Essential, not in YDL homozygous screen data)
Experiment_Type Biochemical Activity
Citation Sidorova JM and Breeden LL (1997) Rad53-dependent phosphorylation of Swi6 and down-regulation of CLN1 and CLN2 transcription occur in response to DNA damage in Saccharomyces cerevisiae. Genes Dev 11(22):3032-45
47) Feature_Name YLR033W RSC58 (Essential, not in YDL homozygous screen data)
Experiment_Type Two-hybrid
Citation Taneda T and Kikuchi A (2004) Genetic analysis of RSC58, which encodes a component of a yeast chromatin remodeling complex, and interacts with the transcription factor Swi6. Mol Genet Genomics 271(4):479-89
48) Feature_Name YHL034C SBP1
Experiment_Type Affinity Capture-RNA
Citation Mitchell SF, et al. (2013) Global analysis of yeast mRNPs. Nat Struct Mol Biol 20(1):127-33
49) Feature_Name YOL113W SKM1
Experiment_Type Biochemical Activity
Citation Ptacek J, et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438(7068):679-84
50) Feature_Name YHR030C SLT2
Experiment_Type Biochemical Activity
Citation Madden K, et al. (1997) SBF cell cycle regulator as a target of the yeast PKC-MAP kinase pathway. Science 275(5307):1781-4
51) Feature_Name YHR030C SLT2
Experiment_Type Affinity Capture-Western
Citation Madden K, et al. (1997) SBF cell cycle regulator as a target of the yeast PKC-MAP kinase pathway. Science 275(5307):1781-4
52) Feature_Name YHR030C SLT2
Experiment_Type Reconstituted Complex
Citation Baetz K, et al. (2001) Transcriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4. Mol Cell Biol 21(19):6515-28
53) Feature_Name YDR477W SNF1
Experiment_Type Affinity Capture-Western
Citation Pessina S, et al. (2010) Snf1/AMPK promotes S-phase entrance by controlling CLB5 transcription in budding yeast. Cell Cycle 9(11):2189-200
54) Feature_Name YDR477W SNF1
Experiment_Type Affinity Capture-Western
Citation Pessina S, et al. (2010) Snf1/AMPK promotes S-phase entrance by controlling CLB5 transcription in budding yeast. Cell Cycle 9(11):2189-200
55) Feature_Name YDR477W SNF1
Experiment_Type Affinity Capture-Western
Citation Busnelli S, et al. (2013) Snf1/AMPK promotes SBF and MBF-dependent transcription in budding yeast. Biochim Biophys Acta 1833(12):3254-64
56) Feature_Name YDR477W SNF1
Experiment_Type Affinity Capture-Western
Citation Busnelli S, et al. (2013) Snf1/AMPK promotes SBF and MBF-dependent transcription in budding yeast. Biochim Biophys Acta 1833(12):3254-64
57) Feature_Name YJL127C SPT10
Experiment_Type Affinity Capture-MS
Citation Kurat CF, et al. (2014) Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation. Proc Natl Acad Sci U S A 111(39):14124-9
58) Feature_Name YER148W SPT15 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-MS
Citation Sanders SL, et al. (2002) Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol 22(13):4723-38
59) Feature_Name YGL207W SPT16 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-Western
Citation Takahata S, et al. (2009) FACT and Asf1 regulate nucleosome dynamics and coactivator binding at the HO promoter. Mol Cell 34(4):405-15
60) Feature_Name YGL207W SPT16 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-Western
Citation Takahata S, et al. (2009) The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters. EMBO J 28(21):3378-89
61) Feature_Name YNL309W STB1
Experiment_Type Reconstituted Complex
Citation Costanzo M, et al. (2003) G1 transcription factors are differentially regulated in Saccharomyces cerevisiae by the Swi6-binding protein Stb1. Mol Cell Biol 23(14):5064-77
62) Feature_Name YNL309W STB1
Experiment_Type Affinity Capture-Western
Citation de Bruin RA, et al. (2008) Stb1 collaborates with other regulators to modulate the G1-specific transcriptional circuit. Mol Cell Biol 28(22):6919-28
63) Feature_Name YNL309W STB1
Experiment_Type Affinity Capture-Western
Citation Ho Y, et al. (1999) Regulation of transcription at the Saccharomyces cerevisiae start transition by Stb1, a Swi6-binding protein. Mol Cell Biol 19(8):5267-78
64) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Imamura Y, et al. (2014) 3,6-Epidioxy-1,10-bisaboladiene inhibits G1 -specific transcription through Swi4/Swi6 and Mbp1/Swi6 via the Hog1 stress pathway in yeast. FEBS J 281(20):4612-21
65) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Travesa A, et al. (2013) Repression of G1/S transcription is mediated via interaction of the GTB motifs of Nrm1 and Whi5 with Swi6. Mol Cell Biol 33(8):1476-86
66) Feature_Name YER111C SWI4
Experiment_Type PCA
Citation Ear PH and Michnick SW (2009) A general life-death selection strategy for dissecting protein functions. Nat Methods 6(11):813-6
67) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Harris MR, et al. (2013) Binding specificity of the G1/S transcriptional regulators in budding yeast. PLoS One 8(4):e61059
68) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Harris MR, et al. (2013) Binding specificity of the G1/S transcriptional regulators in budding yeast. PLoS One 8(4):e61059
69) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Kaluarachchi Duffy S, et al. (2012) Exploring the yeast acetylome using functional genomics. Cell 149(4):936-48
70) Feature_Name YER111C SWI4
Experiment_Type Reconstituted Complex
Citation Andrews BJ and Herskowitz I (1989) Identification of a DNA binding factor involved in cell-cycle control of the yeast HO gene. Cell 57(1):21-9
71) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Eriksson PR, et al. (2011) Spt10 and Swi4 Control the Timing of Histone H2A/H2B Gene Activation in Budding Yeast. Mol Cell Biol 31(3):557-72
72) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Ear PH and Michnick SW (2009) A general life-death selection strategy for dissecting protein functions. Nat Methods 6(11):813-6
73) Feature_Name YER111C SWI4
Experiment_Type Reconstituted Complex
Citation Ear PH and Michnick SW (2009) A general life-death selection strategy for dissecting protein functions. Nat Methods 6(11):813-6
74) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-MS
Citation Gavin AC, et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 440(7084):631-6
75) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-MS
Citation Gavin AC, et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 440(7084):631-6
76) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-MS
Citation Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43
77) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Wijnen H, et al. (2002) The G(1) cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6. Mol Cell Biol 22(12):4402-18
78) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Wijnen H, et al. (2002) The G(1) cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6. Mol Cell Biol 22(12):4402-18
79) Feature_Name YER111C SWI4
Experiment_Type Affinity Capture-Western
Citation Siegmund RF and Nasmyth KA (1996) The Saccharomyces cerevisiae Start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6. Mol Cell Biol 16(6):2647-55
80) Feature_Name YER111C SWI4
Experiment_Type Reconstituted Complex
Citation Andrews BJ and Moore LA (1992) Interaction of the yeast Swi4 and Swi6 cell cycle regulatory proteins in vitro. Proc Natl Acad Sci U S A 89(24):11852-6
81) Feature_Name YER111C SWI4
Experiment_Type Reconstituted Complex
Citation Baetz K and Andrews B (1999) Regulation of cell cycle transcription factor Swi4 through auto-inhibition of DNA binding. Mol Cell Biol 19(10):6729-41
82) Feature_Name YER111C SWI4
Experiment_Type Reconstituted Complex
Citation Ewaskow SP, et al. (1998) Mutation and modeling analysis of the Saccharomyces cerevisiae Swi6 ankyrin repeats. Biochemistry 37(13):4437-50
83) Feature_Name YDR145W TAF12 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-MS
Citation Sanders SL, et al. (2002) Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol 22(13):4723-38
84) Feature_Name YMR227C TAF7 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-MS
Citation Sanders SL, et al. (2002) Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol 22(13):4723-38
85) Feature_Name YML114C TAF8 (Essential, not in YDL homozygous screen data)
Experiment_Type Affinity Capture-MS
Citation Sanders SL, et al. (2002) Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol 22(13):4723-38
86) Feature_Name YOR083W WHI5
Experiment_Type Reconstituted Complex
Citation Costanzo M, et al. (2004) CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast. Cell 117(7):899-913
87) Feature_Name YOR083W WHI5
Experiment_Type Affinity Capture-Western
Citation de Bruin RA, et al. (2004) Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5. Cell 117(7):887-98
88) Feature_Name YOR083W WHI5
Experiment_Type Affinity Capture-MS
Citation de Bruin RA, et al. (2004) Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5. Cell 117(7):887-98
89) Feature_Name YOR083W WHI5
Experiment_Type Affinity Capture-MS
Citation Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43
90) Feature_Name YOR083W WHI5
Experiment_Type Affinity Capture-Western
Citation Costanzo M, et al. (2004) CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast. Cell 117(7):899-913
91) Feature_Name YOR083W WHI5
Experiment_Type Affinity Capture-Western
Citation Harris MR, et al. (2013) Binding specificity of the G1/S transcriptional regulators in budding yeast. PLoS One 8(4):e61059
92) Feature_Name YOR083W WHI5
Experiment_Type Affinity Capture-Western
Citation Travesa A, et al. (2013) Repression of G1/S transcription is mediated via interaction of the GTB motifs of Nrm1 and Whi5 with Swi6. Mol Cell Biol 33(8):1476-86
93) Feature_Name YOL131W YOL131W
Experiment_Type Two-hybrid
Citation Ito T, et al. (2001) A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci U S A 98(8):4569-74

SWI6 (YLR182W) displays 490 Genetic Interaction(s) as listed below

Show/Hide +/- Genetic Interaction(s)
1) Feature_Name YMR056C AAC1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
2) Feature_Name YLR131C ACE2
Experiment_Type Synthetic Growth Defect
Citation Batenchuk C, et al. (2010) Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. BMC Genomics 11():493
3) Feature_Name YDR448W ADA2
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
4) Feature_Name YER017C AFG3
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
5) Feature_Name YGL071W AFT1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
6) Feature_Name YMR092C AIP1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
7) Feature_Name YBR059C AKL1
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
8) Feature_Name YPL227C ALG5
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
9) Feature_Name YBL009W ALK2
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
10) Feature_Name YEL036C ANP1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
11) Feature_Name YOL062C APM4
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
12) Feature_Name YHR013C ARD1
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
13) Feature_Name YHR013C ARD1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
14) Feature_Name YDL192W ARF1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
15) Feature_Name YOR141C ARP8
Experiment_Type Phenotypic Enhancement
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
16) Feature_Name YOR141C ARP8
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
17) Feature_Name YKL185W ASH1
Experiment_Type Synthetic Growth Defect
Citation Batenchuk C, et al. (2010) Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. BMC Genomics 11():493
18) Feature_Name YOR113W AZF1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
19) Feature_Name YJL095W BCK1
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
20) Feature_Name YJL095W BCK1
Experiment_Type Synthetic Growth Defect
Citation Corcoles-Saez I, et al. (2012) Low temperature highlights the functional role of the cell wall integrity pathway in the regulation of growth in Saccharomyces cerevisiae. Biochem J 446(3):477-88
21) Feature_Name YBR200W BEM1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
22) Feature_Name YPL115C BEM3
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
23) Feature_Name YER016W BIM1
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2004) A robust toolkit for functional profiling of the yeast genome. Mol Cell 16(3):487-96
24) Feature_Name YER177W BMH1
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
25) Feature_Name YPL217C BMS1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
26) Feature_Name YNL271C BNI1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
27) Feature_Name YNL233W BNI4
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
28) Feature_Name YNL233W BNI4
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
29) Feature_Name YER114C BOI2
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
30) Feature_Name YDL074C BRE1
Experiment_Type Synthetic Lethality
Citation Xiao T, et al. (2005) Histone H2B ubiquitylation is associated with elongating RNA polymerase II. Mol Cell Biol 25(2):637-51
31) Feature_Name YDL074C BRE1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
32) Feature_Name YDL074C BRE1
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
33) Feature_Name YLR015W BRE2
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
34) Feature_Name YNR051C BRE5
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
35) Feature_Name YFL025C BST1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
36) Feature_Name YOR026W BUB3
Experiment_Type Phenotypic Enhancement
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
37) Feature_Name YOR026W BUB3
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
38) Feature_Name YGL174W BUD13
Experiment_Type Positive Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
39) Feature_Name YAR014C BUD14
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
40) Feature_Name YAL021C CCR4
Experiment_Type Synthetic Lethality
Citation Manukyan A, et al. (2008) Ccr4 Alters Cell Size in Yeast by Modulating the Timing of CLN1 and CLN2 Expression. Genetics 179(1):345-57
41) Feature_Name YAL021C CCR4
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
42) Feature_Name YMR038C CCS1
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
43) Feature_Name YCR002C CDC10
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
44) Feature_Name YHR107C CDC12 (Essential, not in YDL homozygous screen data)
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
45) Feature_Name YDL220C CDC13 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Growth Defect
Citation Addinall SG, et al. (2008) A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66
46) Feature_Name YJL194W CDC6 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Archambault V, et al. (2005) Disruption of mechanisms that prevent rereplication triggers a DNA damage response. Mol Cell Biol 25(15):6707-21
47) Feature_Name YLR418C CDC73
Experiment_Type Synthetic Growth Defect
Citation Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
48) Feature_Name YLR418C CDC73
Experiment_Type Synthetic Growth Defect
Citation Krogan NJ, et al. (2003) A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell 12(6):1565-76
49) Feature_Name YGL003C CDH1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
50) Feature_Name YPL228W CET1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
51) Feature_Name YCL064C CHA1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
52) Feature_Name YER164W CHD1
Experiment_Type Phenotypic Suppression
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
53) Feature_Name YPL008W CHL1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
54) Feature_Name YDR254W CHL4
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
55) Feature_Name YDR254W CHL4
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
56) Feature_Name YJL099W CHS6
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
57) Feature_Name YEL061C CIN8
Experiment_Type Synthetic Lethality
Citation Shohat-Tal A and Eshel D (2011) Cell cycle regulators interact with pathways that modulate microtubule stability in Saccharomyces cerevisiae. Eukaryot Cell 10(12):1705-13
58) Feature_Name YEL061C CIN8
Experiment_Type Synthetic Lethality
Citation Shohat-Tal A and Eshel D (2011) Cell cycle regulators interact with pathways that modulate microtubule stability in Saccharomyces cerevisiae. Eukaryot Cell 10(12):1705-13
59) Feature_Name YOR039W CKB2
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
60) Feature_Name YNL298W CLA4
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
61) Feature_Name YNL298W CLA4
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
62) Feature_Name YNL298W CLA4
Experiment_Type Negative Genetic
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
63) Feature_Name YNL298W CLA4
Experiment_Type Dosage Growth Defect
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
64) Feature_Name YNL298W CLA4
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
65) Feature_Name YGR108W CLB1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
66) Feature_Name YPR119W CLB2
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
67) Feature_Name YPR120C CLB5
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
68) Feature_Name YPR120C CLB5
Experiment_Type Synthetic Lethality
Citation Queralt E and Igual JC (2005) Functional connection between the Clb5 cyclin, the protein kinase C pathway and the Swi4 transcription factor in Saccharomyces cerevisiae. Genetics 171(4):1485-98
69) Feature_Name YPR120C CLB5
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
70) Feature_Name YMR199W CLN1
Experiment_Type Dosage Rescue
Citation Takahata S, et al. (2009) The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters. EMBO J 28(21):3378-89
71) Feature_Name YMR199W CLN1
Experiment_Type Dosage Rescue
Citation Wijnen H and Futcher B (1999) Genetic analysis of the shared role of CLN3 and BCK2 at the G(1)-S transition in Saccharomyces cerevisiae. Genetics 153(3):1131-43
72) Feature_Name YPL256C CLN2
Experiment_Type Dosage Rescue
Citation Wijnen H and Futcher B (1999) Genetic analysis of the shared role of CLN3 and BCK2 at the G(1)-S transition in Saccharomyces cerevisiae. Genetics 153(3):1131-43
73) Feature_Name YPL256C CLN2
Experiment_Type Dosage Rescue
Citation Takahata S, et al. (2009) The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters. EMBO J 28(21):3378-89
74) Feature_Name YPL256C CLN2
Experiment_Type Dosage Rescue
Citation Queralt E and Igual JC (2004) Functional distinction between Cln1p and Cln2p cyclins in the control of the Saccharomyces cerevisiae mitotic cycle. Genetics 168(1):129-40
75) Feature_Name YPL256C CLN2
Experiment_Type Dosage Rescue
Citation Quilis I and Igual JC (2012) Molecular basis of the functional distinction between Cln1 and Cln2 cyclins. Cell Cycle 11(16):3117-31
76) Feature_Name YAL040C CLN3
Experiment_Type Synthetic Rescue
Citation Wijnen H, et al. (2002) The G(1) cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6. Mol Cell Biol 22(12):4402-18
77) Feature_Name YAL040C CLN3
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
78) Feature_Name YER157W COG3 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
79) Feature_Name YNL027W CRZ1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
80) Feature_Name YNR010W CSE2
Experiment_Type Synthetic Growth Defect
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
81) Feature_Name YNR010W CSE2
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
82) Feature_Name YCR086W CSM1
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
83) Feature_Name YBR042C CST26
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
84) Feature_Name YMR078C CTF18
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
85) Feature_Name YMR078C CTF18
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
86) Feature_Name YPR135W CTF4
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
87) Feature_Name YPR135W CTF4
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
88) Feature_Name YHR191C CTF8
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
89) Feature_Name YHR191C CTF8
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
90) Feature_Name YHR191C CTF8
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
91) Feature_Name YHR191C CTF8
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
92) Feature_Name YKL139W CTK1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
93) Feature_Name YKL139W CTK1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
94) Feature_Name YJL006C CTK2
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
95) Feature_Name YML112W CTK3
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
96) Feature_Name YML112W CTK3
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
97) Feature_Name YBR112C CYC8
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
98) Feature_Name YIR023W DAL81
Experiment_Type Synthetic Growth Defect
Citation Batenchuk C, et al. (2010) Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. BMC Genomics 11():493
99) Feature_Name YOR046C DBP5 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Scarcelli JJ, et al. (2008) Synthetic Genetic Array Analysis in Saccharomyces cerevisiae Provides Evidence for an Interaction Between RAT8/DBP5 and Genes Encoding P-Body Components. Genetics 179(4):1945-55
100) Feature_Name YCL016C DCC1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
101) Feature_Name YCL016C DCC1
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
102) Feature_Name YFL001W DEG1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
103) Feature_Name YFL001W DEG1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
104) Feature_Name YDR411C DFM1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
105) Feature_Name YOR311C DGK1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
106) Feature_Name YKL213C DOA1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
107) Feature_Name YKL213C DOA1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
108) Feature_Name YKL213C DOA1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
109) Feature_Name YDR440W DOT1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
110) Feature_Name YEL070W DSF1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
111) Feature_Name YDL101C DUN1
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
112) Feature_Name YDL101C DUN1
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
113) Feature_Name YDL101C DUN1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
114) Feature_Name YDR359C EAF1
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
115) Feature_Name YPR023C EAF3
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
116) Feature_Name YPR023C EAF3
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
117) Feature_Name YPR023C EAF3
Experiment_Type Positive Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
118) Feature_Name YJR082C EAF6
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
119) Feature_Name YNL136W EAF7
Experiment_Type Synthetic Growth Defect
Citation Mitchell L, et al. (2008) Functional dissection of the NuA4 histone acetyltransferase reveals its role as a genetic hub and that Eaf1 is essential for complex integrity. Mol Cell Biol 28(7):2244-56
120) Feature_Name YNL136W EAF7
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
121) Feature_Name YGR007W ECT1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
122) Feature_Name YPL037C EGD1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
123) Feature_Name YKL160W ELF1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
124) Feature_Name YKL160W ELF1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
125) Feature_Name YKL048C ELM1
Experiment_Type Negative Genetic
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
126) Feature_Name YKL048C ELM1
Experiment_Type Dosage Growth Defect
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
127) Feature_Name YKL048C ELM1
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
128) Feature_Name YKL048C ELM1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
129) Feature_Name YKL048C ELM1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
130) Feature_Name YGR200C ELP2
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
131) Feature_Name YGR200C ELP2
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
132) Feature_Name YGR200C ELP2
Experiment_Type Synthetic Growth Defect
Citation Kong SE, et al. (2005) Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator. J Biol Chem 280(6):4299-306
133) Feature_Name YGR200C ELP2
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
134) Feature_Name YPL086C ELP3
Experiment_Type Synthetic Growth Defect
Citation Kong SE, et al. (2005) Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator. J Biol Chem 280(6):4299-306
135) Feature_Name YPL086C ELP3
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
136) Feature_Name YPL086C ELP3
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
137) Feature_Name YPL086C ELP3
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
138) Feature_Name YPL086C ELP3
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
139) Feature_Name YMR312W ELP6
Experiment_Type Synthetic Growth Defect
Citation Kong SE, et al. (2005) Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator. J Biol Chem 280(6):4299-306
140) Feature_Name YDR512C EMI1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
141) Feature_Name YGL200C EMP24
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
142) Feature_Name YFL024C EPL1 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
143) Feature_Name YHR123W EPT1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
144) Feature_Name YOR244W ESA1 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
145) Feature_Name YOR244W ESA1 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
146) Feature_Name YOR244W ESA1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
147) Feature_Name YJR017C ESS1 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Growth Defect
Citation Atencio D, et al. (2014) The Yeast Ess1 Prolyl Isomerase Controls Swi6 and Whi5 Nuclear Localization. G3 (Bethesda) ()
148) Feature_Name YJR017C ESS1 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Atencio D, et al. (2014) The Yeast Ess1 Prolyl Isomerase Controls Swi6 and Whi5 Nuclear Localization. G3 (Bethesda) ()
149) Feature_Name YJL085W EXO70 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
150) Feature_Name YJL157C FAR1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
151) Feature_Name YKL060C FBA1 (Essential, not in YDL homozygous screen data)
Experiment_Type Dosage Rescue
Citation Flick K and Wittenberg C (2005) Multiple pathways for suppression of mutants affecting G1-specific transcription in Saccharomyces cerevisiae. Genetics 169(1):37-49
152) Feature_Name YMR277W FCP1 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Shohat-Tal A and Eshel D (2011) Cell cycle regulators interact with pathways that modulate microtubule stability in Saccharomyces cerevisiae. Eukaryot Cell 10(12):1705-13
153) Feature_Name YMR144W FDO1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
154) Feature_Name YBR101C FES1
Experiment_Type Phenotypic Suppression
Citation Shaner L, et al. (2008) The Hsp110 protein chaperone Sse1 is required for yeast cell wall integrity and morphogenesis. Curr Genet 54(1):1-11
155) Feature_Name YFL041W FET5
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
156) Feature_Name YNR047W FPK1
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
157) Feature_Name YIL097W FYV10
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
158) Feature_Name YGL195W GCN1
Experiment_Type Positive Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
159) Feature_Name YNL199C GCR2
Experiment_Type Positive Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
160) Feature_Name YNL199C GCR2
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
161) Feature_Name YNL199C GCR2
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
162) Feature_Name YDL215C GDH2
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
163) Feature_Name YGL020C GET1
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
164) Feature_Name YGL020C GET1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
165) Feature_Name YER083C GET2
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
166) Feature_Name YDR309C GIC2
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
167) Feature_Name YEL003W GIM4
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
168) Feature_Name YDR507C GIN4
Experiment_Type Dosage Rescue
Citation Flick K and Wittenberg C (2005) Multiple pathways for suppression of mutants affecting G1-specific transcription in Saccharomyces cerevisiae. Genetics 169(1):37-49
169) Feature_Name YDR507C GIN4
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
170) Feature_Name YDR507C GIN4
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
171) Feature_Name YDR507C GIN4
Experiment_Type Negative Genetic
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
172) Feature_Name YDR507C GIN4
Experiment_Type Dosage Growth Defect
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
173) Feature_Name YPL137C GIP3
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
174) Feature_Name YER133W GLC7 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
175) Feature_Name YFL027C GYP8
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
176) Feature_Name YGL237C HAP2
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
177) Feature_Name YNL021W HDA1
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
178) Feature_Name YDR295C HDA2
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
179) Feature_Name YMR207C HFA1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
180) Feature_Name YER052C HOM3
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
181) Feature_Name YGL194C HOS2
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
182) Feature_Name YKL101W HSL1
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
183) Feature_Name YOL068C HST1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
184) Feature_Name YOL012C HTZ1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
185) Feature_Name YDL245C HXT15
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
186) Feature_Name YEL034W HYP2 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
187) Feature_Name YNL215W IES2
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
188) Feature_Name YLR384C IKI3
Experiment_Type Synthetic Growth Defect
Citation Kong SE, et al. (2005) Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator. J Biol Chem 280(6):4299-306
189) Feature_Name YDR315C IPK1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
190) Feature_Name YOL081W IRA2
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
191) Feature_Name YER019W ISC1
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
192) Feature_Name YGL133W ITC1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
193) Feature_Name YDR497C ITR1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
194) Feature_Name YKL032C IXR1
Experiment_Type Synthetic Growth Defect
Citation Batenchuk C, et al. (2010) Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. BMC Genomics 11():493
195) Feature_Name YPR061C JID1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
196) Feature_Name YDR017C KCS1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
197) Feature_Name YBL063W KIP1
Experiment_Type Synthetic Lethality
Citation Shohat-Tal A and Eshel D (2011) Cell cycle regulators interact with pathways that modulate microtubule stability in Saccharomyces cerevisiae. Eukaryot Cell 10(12):1705-13
198) Feature_Name YNL322C KRE1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
199) Feature_Name YOR336W KRE5 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
200) Feature_Name YGR040W KSS1
Experiment_Type Dosage Growth Defect
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
201) Feature_Name YOR123C LEO1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
202) Feature_Name YOR123C LEO1
Experiment_Type Phenotypic Enhancement
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
203) Feature_Name YPL055C LGE1
Experiment_Type Synthetic Lethality
Citation Xiao T, et al. (2005) Histone H2B ubiquitylation is associated with elongating RNA polymerase II. Mol Cell Biol 25(2):637-51
204) Feature_Name YPL055C LGE1
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
205) Feature_Name YPL055C LGE1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
206) Feature_Name YHR081W LRP1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
207) Feature_Name YHR081W LRP1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
208) Feature_Name YDR439W LRS4
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
209) Feature_Name YJL124C LSM1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
210) Feature_Name YJL124C LSM1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
211) Feature_Name YER112W LSM4 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
212) Feature_Name YDR378C LSM6
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
213) Feature_Name YDL056W MBP1
Experiment_Type Dosage Rescue
Citation Bouquin N, et al. (1999) Association of the cell cycle transcription factor Mbp1 with the Skn7 response regulator in budding yeast. Mol Biol Cell 10(10):3389-400
214) Feature_Name YDL056W MBP1
Experiment_Type Synthetic Rescue
Citation Bouquin N, et al. (1999) Association of the cell cycle transcription factor Mbp1 with the Skn7 response regulator in budding yeast. Mol Biol Cell 10(10):3389-400
215) Feature_Name YDL003W MCD1 (Essential, not in YDL homozygous screen data)
Experiment_Type Negative Genetic
Citation McLellan JL, et al. (2012) Synthetic Lethality of Cohesins with PARPs and Replication Fork Mediators. PLoS Genet 8(3):e1002574
216) Feature_Name YPR046W MCM16
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
217) Feature_Name YDR318W MCM21
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
218) Feature_Name YJR135C MCM22
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
219) Feature_Name YPR070W MED1
Experiment_Type Synthetic Growth Defect
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
220) Feature_Name YPR070W MED1
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
221) Feature_Name YOR351C MEK1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
222) Feature_Name YOR351C MEK1
Experiment_Type Positive Genetic
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
223) Feature_Name YML062C MFT1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
224) Feature_Name YGL035C MIG1
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
225) Feature_Name YPR164W MMS1
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
226) Feature_Name YLR320W MMS22
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
227) Feature_Name YOR350C MNE1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
228) Feature_Name YDR245W MNN10
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
229) Feature_Name YDR245W MNN10
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
230) Feature_Name YJL183W MNN11
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
231) Feature_Name YMR070W MOT3
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
232) Feature_Name YKL059C MPE1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
233) Feature_Name YGL178W MPT5
Experiment_Type Synthetic Lethality
Citation Kaeberlein M and Guarente L (2002) Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity. Genetics 160(1):83-95
234) Feature_Name YCL061C MRC1
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
235) Feature_Name YMR224C MRE11
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
236) Feature_Name YOL116W MSN1
Experiment_Type Dosage Rescue
Citation Sidorova J and Breeden L (1999) The MSN1 and NHP6A genes suppress SWI6 defects in Saccharomyces cerevisiae. Genetics 151(1):45-55
237) Feature_Name YKL062W MSN4
Experiment_Type Synthetic Growth Defect
Citation Batenchuk C, et al. (2010) Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. BMC Genomics 11():493
238) Feature_Name YDR335W MSN5
Experiment_Type Synthetic Lethality
Citation Queralt E and Igual JC (2003) Cell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling. Mol Cell Biol 23(9):3126-40
239) Feature_Name YDR335W MSN5
Experiment_Type Synthetic Lethality
Citation Alepuz PM, et al. (1999) The Saccharomyces cerevisiae RanGTP-binding protein msn5p is involved in different signal transduction pathways. Genetics 153(3):1219-31
240) Feature_Name YDR386W MUS81
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
241) Feature_Name YKR048C NAP1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
242) Feature_Name YKR048C NAP1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
243) Feature_Name YDL040C NAT1
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
244) Feature_Name YDR162C NBP2
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
245) Feature_Name YPR052C NHP6A
Experiment_Type Dosage Rescue
Citation Sidorova J and Breeden L (1999) The MSN1 and NHP6A genes suppress SWI6 defects in Saccharomyces cerevisiae. Genetics 151(1):45-55
246) Feature_Name YBR089C-A NHP6B
Experiment_Type Dosage Rescue
Citation Sidorova J and Breeden L (1999) The MSN1 and NHP6A genes suppress SWI6 defects in Saccharomyces cerevisiae. Genetics 151(1):45-55
247) Feature_Name YDR432W NPL3
Experiment_Type Synthetic Growth Defect
Citation Moehle EA, et al. (2012) The Yeast SR-Like Protein Npl3 Links Chromatin Modification to mRNA Processing. PLoS Genet 8(11):e1003101
248) Feature_Name YDL116W NUP84
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
249) Feature_Name YGL151W NUT1
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
250) Feature_Name YGL055W OLE1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
251) Feature_Name YHL020C OPI1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
252) Feature_Name YPR194C OPT2
Experiment_Type Synthetic Lethality
Citation Elbaz-Alon Y, et al. (2014) The yeast oligopeptide transporter Opt2 is localized to peroxisomes and affects glutathione redox homeostasis. FEMS Yeast Res 14(7):1055-67
253) Feature_Name YBR060C ORC2 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
254) Feature_Name YHR118C ORC6 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Archambault V, et al. (2005) Disruption of mechanisms that prevent rereplication triggers a DNA damage response. Mol Cell Biol 25(15):6707-21
255) Feature_Name YOR103C OST2 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
256) Feature_Name YER165W PAB1 (Essential, not in YDL homozygous screen data)
Experiment_Type Dosage Rescue
Citation Flick K and Wittenberg C (2005) Multiple pathways for suppression of mutants affecting G1-specific transcription in Saccharomyces cerevisiae. Genetics 169(1):37-49
257) Feature_Name YBR279W PAF1
Experiment_Type Synthetic Lethality
Citation Porter SE, et al. (2002) The yeast pafl-rNA polymerase II complex is required for full expression of a subset of cell cycle-regulated genes. Eukaryot Cell 1(5):830-42
258) Feature_Name YOL115W PAP2
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
259) Feature_Name YCR077C PAT1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
260) Feature_Name YIL071C PCI8
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
261) Feature_Name YKR097W PCK1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
262) Feature_Name YNL289W PCL1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
263) Feature_Name YPL219W PCL8
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
264) Feature_Name YER178W PDA1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
265) Feature_Name YOR122C PFY1 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Growth Defect
Citation Figley MD, et al. (2014) Profilin 1 Associates with Stress Granules and ALS-Linked Mutations Alter Stress Granule Dynamics. J Neurosci 34(24):8083-97
266) Feature_Name YGL025C PGD1
Experiment_Type Synthetic Growth Defect
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
267) Feature_Name YGL025C PGD1
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
268) Feature_Name YGR132C PHB1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
269) Feature_Name YDL106C PHO2
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
270) Feature_Name YOL001W PHO80
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
271) Feature_Name YPL268W PLC1
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
272) Feature_Name YDR501W PLM2
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
273) Feature_Name YML069W POB3 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Takahata S, et al. (2009) The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters. EMBO J 28(21):3378-89
274) Feature_Name YJR043C POL32
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
275) Feature_Name YEL055C POL5 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
276) Feature_Name YNR052C POP2
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
277) Feature_Name YDL134C PPH21
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
278) Feature_Name YER013W PRP22 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
279) Feature_Name YLR019W PSR2
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
280) Feature_Name YNL201C PSY2
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
281) Feature_Name YNL201C PSY2
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
282) Feature_Name YDL006W PTC1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
283) Feature_Name YCR066W RAD18
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
284) Feature_Name YKL113C RAD27
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
285) Feature_Name YKL113C RAD27
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
286) Feature_Name YNL250W RAD50
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
287) Feature_Name YER095W RAD51
Experiment_Type Positive Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
288) Feature_Name YER095W RAD51
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
289) Feature_Name YML032C RAD52
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
290) Feature_Name YML032C RAD52
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
291) Feature_Name YGL163C RAD54
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
292) Feature_Name YGL163C RAD54
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
293) Feature_Name YDR076W RAD55
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
294) Feature_Name YGL058W RAD6
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
295) Feature_Name YGL058W RAD6
Experiment_Type Synthetic Lethality
Citation Xiao T, et al. (2005) Histone H2B ubiquitylation is associated with elongating RNA polymerase II. Mol Cell Biol 25(2):637-51
296) Feature_Name YNL216W RAP1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
297) Feature_Name YNL216W RAP1 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Rescue
Citation Laman H, et al. (1995) Disturbance of normal cell cycle progression enhances the establishment of transcriptional silencing in Saccharomyces cerevisiae. Mol Cell Biol 15(7):3608-17
298) Feature_Name YLR248W RCK2
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
299) Feature_Name YMR075W RCO1
Experiment_Type Positive Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
300) Feature_Name YMR075W RCO1
Experiment_Type Phenotypic Suppression
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
301) Feature_Name YIL139C REV7
Experiment_Type Dosage Rescue
Citation Gong J and Siede W (2009) SBF transcription factor complex positively regulates UV mutagenesis in Saccharomyces cerevisiae. Biochem Biophys Res Commun 379(4):1009-14
302) Feature_Name YDR091C RLI1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
303) Feature_Name YPL089C RLM1
Experiment_Type Phenotypic Enhancement
Citation LaFayette SL, et al. (2010) PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90.LID - e1001069 [pii] PLoS Pathog 6(8)
304) Feature_Name YGR044C RME1
Experiment_Type Dosage Rescue
Citation Wijnen H and Futcher B (1999) Genetic analysis of the shared role of CLN3 and BCK2 at the G(1)-S transition in Saccharomyces cerevisiae. Genetics 153(3):1131-43
305) Feature_Name YGR044C RME1
Experiment_Type Synthetic Lethality
Citation Toone WM, et al. (1995) Rme1, a negative regulator of meiosis, is also a positive activator of G1 cyclin gene expression. EMBO J 14(23):5824-32
306) Feature_Name YGR070W ROM1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
307) Feature_Name YBL093C ROX3
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
308) Feature_Name YDR156W RPA14
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
309) Feature_Name YDR156W RPA14
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
310) Feature_Name YDR156W RPA14
Experiment_Type Phenotypic Enhancement
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
311) Feature_Name YNL248C RPA49
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
312) Feature_Name YNL330C RPD3
Experiment_Type Synthetic Lethality
Citation Vannier D, et al. (2001) A role for Sds3p, a component of the Rpd3p/Sin3p deacetylase complex, in maintaining cellular integrity in Saccharomyces cerevisiae. Mol Genet Genomics 265(3):560-8
313) Feature_Name YHR200W RPN10
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
314) Feature_Name YHR200W RPN10
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
315) Feature_Name YHR200W RPN10
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
316) Feature_Name YDL020C RPN4
Experiment_Type Synthetic Growth Defect
Citation Batenchuk C, et al. (2010) Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. BMC Genomics 11():493
317) Feature_Name YDL020C RPN4
Experiment_Type Positive Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
318) Feature_Name YDL020C RPN4
Experiment_Type Phenotypic Suppression
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
319) Feature_Name YOR116C RPO31 (Essential, not in YDL homozygous screen data)
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
320) Feature_Name YOL039W RPP2A
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
321) Feature_Name YOR001W RRP6
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
322) Feature_Name YGL244W RTF1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
323) Feature_Name YOL067C RTG1
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
324) Feature_Name YOL067C RTG1
Experiment_Type Positive Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
325) Feature_Name YBL103C RTG3
Experiment_Type Synthetic Growth Defect
Citation Batenchuk C, et al. (2010) Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. BMC Genomics 11():493
326) Feature_Name YJL047C RTT101
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
327) Feature_Name YHR154W RTT107
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
328) Feature_Name YHR154W RTT107
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
329) Feature_Name YLL002W RTT109
Experiment_Type Synthetic Growth Defect
Citation Fillingham J, et al. (2008) Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109. Mol Cell Biol 28(13):4342-53
330) Feature_Name YLL002W RTT109
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
331) Feature_Name YPL235W RVB2 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
332) Feature_Name YCR009C RVS161
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
333) Feature_Name YDR388W RVS167
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
334) Feature_Name YBR095C RXT2
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
335) Feature_Name YDR159W SAC3
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
336) Feature_Name YDR159W SAC3
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
337) Feature_Name YDR180W SCC2 (Essential, not in YDL homozygous screen data)
Experiment_Type Negative Genetic
Citation McLellan JL, et al. (2012) Synthetic Lethality of Cohesins with PARPs and Replication Fork Mediators. PLoS Genet 8(3):e1002574
338) Feature_Name YDR180W SCC2 (Essential, not in YDL homozygous screen data)
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
339) Feature_Name YMR214W SCJ1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
340) Feature_Name YIL084C SDS3
Experiment_Type Synthetic Lethality
Citation Vannier D, et al. (2001) A role for Sds3p, a component of the Rpd3p/Sin3p deacetylase complex, in maintaining cellular integrity in Saccharomyces cerevisiae. Mol Genet Genomics 265(3):560-8
341) Feature_Name YIR022W SEC11 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
342) Feature_Name YBL050W SEC17 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
343) Feature_Name YLR268W SEC22
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
344) Feature_Name YGR009C SEC9 (Essential, not in YDL homozygous screen data)
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
345) Feature_Name YDR363W-A SEM1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
346) Feature_Name YDR363W-A SEM1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
347) Feature_Name YDR363W-A SEM1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
348) Feature_Name YGR208W SER2
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
349) Feature_Name YGR208W SER2
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
350) Feature_Name YJL105W SET4
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
351) Feature_Name YGL066W SGF73
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
352) Feature_Name YBL058W SHP1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
353) Feature_Name YDL225W SHS1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
354) Feature_Name YLR079W SIC1
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
355) Feature_Name YOL004W SIN3
Experiment_Type Synthetic Lethality
Citation Vannier D, et al. (2001) A role for Sds3p, a component of the Rpd3p/Sin3p deacetylase complex, in maintaining cellular integrity in Saccharomyces cerevisiae. Mol Genet Genomics 265(3):560-8
356) Feature_Name YNL236W SIN4
Experiment_Type Synthetic Rescue
Citation Lycan D, et al. (1994) Differential effects of Cdc68 on cell cycle-regulated promoters in Saccharomyces cerevisiae. Mol Cell Biol 14(11):7455-65
357) Feature_Name YNL236W SIN4
Experiment_Type Synthetic Rescue
Citation Yu Y, et al. (2000) Architectural transcription factors and the SAGA complex function in parallel pathways to activate transcription. Mol Cell Biol 20(7):2350-7
358) Feature_Name YNL236W SIN4
Experiment_Type Synthetic Growth Defect
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
359) Feature_Name YNL236W SIN4
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
360) Feature_Name YNL257C SIP3
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
361) Feature_Name YKR101W SIR1
Experiment_Type Synthetic Rescue
Citation Laman H, et al. (1995) Disturbance of normal cell cycle progression enhances the establishment of transcriptional silencing in Saccharomyces cerevisiae. Mol Cell Biol 15(7):3608-17
362) Feature_Name YDL042C SIR2
Experiment_Type Synthetic Growth Defect
Citation Liu B, et al. (2010) The Polarisome Is Required for Segregation and Retrograde Transport of Protein Aggregates. Cell 140(2):257-267
363) Feature_Name YHR206W SKN7
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
364) Feature_Name YMR216C SKY1
Experiment_Type Negative Genetic
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
365) Feature_Name YBL007C SLA1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
366) Feature_Name YHR030C SLT2
Experiment_Type Synthetic Growth Defect
Citation Corcoles-Saez I, et al. (2012) Low temperature highlights the functional role of the cell wall integrity pathway in the regulation of growth in Saccharomyces cerevisiae. Biochem J 446(3):477-88
367) Feature_Name YDL013W SLX5
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
368) Feature_Name YER116C SLX8
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
369) Feature_Name YGR081C SLX9
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
370) Feature_Name YJL074C SMC3 (Essential, not in YDL homozygous screen data)
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
371) Feature_Name YDR477W SNF1
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
372) Feature_Name YGL115W SNF4
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
373) Feature_Name YJR104C SOD1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
374) Feature_Name YGL127C SOH1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
375) Feature_Name YGL127C SOH1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
376) Feature_Name YEL031W SPF1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
377) Feature_Name YPL138C SPP1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
378) Feature_Name YGL207W SPT16 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Rescue
Citation Lycan D, et al. (1994) Differential effects of Cdc68 on cell cycle-regulated promoters in Saccharomyces cerevisiae. Mol Cell Biol 14(11):7455-65
379) Feature_Name YER161C SPT2
Experiment_Type Phenotypic Suppression
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
380) Feature_Name YER161C SPT2
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
381) Feature_Name YMR179W SPT21
Experiment_Type Synthetic Rescue
Citation Hess D and Winston F (2005) Evidence that Spt10 and Spt21 of Saccharomyces cerevisiae play distinct roles in vivo and functionally interact with MCB-binding factor, SCB-binding factor and Snf1. Genetics 170(1):87-94
382) Feature_Name YDR392W SPT3
Experiment_Type Phenotypic Enhancement
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
383) Feature_Name YDR392W SPT3
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
384) Feature_Name YLR055C SPT8
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
385) Feature_Name YLR055C SPT8
Experiment_Type Synthetic Lethality
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
386) Feature_Name YNL224C SQS1
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
387) Feature_Name YHR041C SRB2
Experiment_Type Synthetic Growth Defect
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
388) Feature_Name YER022W SRB4 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
389) Feature_Name YGR104C SRB5
Experiment_Type Synthetic Growth Defect
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
390) Feature_Name YDR308C SRB7 (Essential, not in YDL homozygous screen data)
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
391) Feature_Name YDR308C SRB7 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Growth Defect
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
392) Feature_Name YCR081W SRB8
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
393) Feature_Name YKR092C SRP40
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
394) Feature_Name YJL092W SRS2
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
395) Feature_Name YDR293C SSD1
Experiment_Type Synthetic Lethality
Citation Kaeberlein M and Guarente L (2002) Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity. Genetics 160(1):83-95
396) Feature_Name YPL106C SSE1
Experiment_Type Synthetic Growth Defect
Citation Shaner L, et al. (2008) The Hsp110 protein chaperone Sse1 is required for yeast cell wall integrity and morphogenesis. Curr Genet 54(1):1-11
397) Feature_Name YPL106C SSE1
Experiment_Type Phenotypic Enhancement
Citation Shaner L, et al. (2008) The Hsp110 protein chaperone Sse1 is required for yeast cell wall integrity and morphogenesis. Curr Genet 54(1):1-11
398) Feature_Name YBR169C SSE2
Experiment_Type Phenotypic Suppression
Citation Shaner L, et al. (2008) The Hsp110 protein chaperone Sse1 is required for yeast cell wall integrity and morphogenesis. Curr Genet 54(1):1-11
399) Feature_Name YDR443C SSN2
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
400) Feature_Name YPL042C SSN3
Experiment_Type Positive Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
401) Feature_Name YPL042C SSN3
Experiment_Type Phenotypic Suppression
Citation Li L, et al. (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171(2):477-88
402) Feature_Name YPL042C SSN3
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
403) Feature_Name YNL309W STB1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
404) Feature_Name YHR178W STB5
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
405) Feature_Name YHR178W STB5
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
406) Feature_Name YMR125W STO1
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
407) Feature_Name YDR310C SUM1
Experiment_Type Positive Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
408) Feature_Name YBR111W-A SUS1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
409) Feature_Name YDR346C SVF1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
410) Feature_Name YPL032C SVL3
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
411) Feature_Name YAL011W SWC3
Experiment_Type Positive Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
412) Feature_Name YGR002C SWC4 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
413) Feature_Name YBR231C SWC5
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
414) Feature_Name YJL176C SWI3
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
415) Feature_Name YER111C SWI4
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
416) Feature_Name YER111C SWI4
Experiment_Type Dosage Rescue
Citation Wijnen H and Futcher B (1999) Genetic analysis of the shared role of CLN3 and BCK2 at the G(1)-S transition in Saccharomyces cerevisiae. Genetics 153(3):1131-43
417) Feature_Name YER111C SWI4
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
418) Feature_Name YER111C SWI4
Experiment_Type Synthetic Growth Defect
Citation Shaner L, et al. (2008) The Hsp110 protein chaperone Sse1 is required for yeast cell wall integrity and morphogenesis. Curr Genet 54(1):1-11
419) Feature_Name YER111C SWI4
Experiment_Type Phenotypic Enhancement
Citation Schulze JM, et al. (2009) Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation. Mol Cell 35(5):626-41
420) Feature_Name YER111C SWI4
Experiment_Type Phenotypic Enhancement
Citation Shaner L, et al. (2008) The Hsp110 protein chaperone Sse1 is required for yeast cell wall integrity and morphogenesis. Curr Genet 54(1):1-11
421) Feature_Name YER111C SWI4
Experiment_Type Dosage Rescue
Citation Sidorova J and Breeden L (1993) Analysis of the SWI4/SWI6 protein complex, which directs G1/S-specific transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(2):1069-77
422) Feature_Name YER111C SWI4
Experiment_Type Dosage Rescue
Citation Breeden L and Mikesell GE (1991) Cell cycle-specific expression of the SWI4 transcription factor is required for the cell cycle regulation of HO transcription. Genes Dev 5(7):1183-90
423) Feature_Name YER111C SWI4
Experiment_Type Synthetic Lethality
Citation Toone WM, et al. (1995) Rme1, a negative regulator of meiosis, is also a positive activator of G1 cyclin gene expression. EMBO J 14(23):5824-32
424) Feature_Name YER111C SWI4
Experiment_Type Synthetic Lethality
Citation Breeden L and Mikesell G (1994) Three independent forms of regulation affect expression of HO, CLN1 and CLN2 during the cell cycle of Saccharomyces cerevisiae. Genetics 138(4):1015-24
425) Feature_Name YMR149W SWP1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
426) Feature_Name YMR236W TAF9 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Macpherson N, et al. (2000) A yeast taf17 mutant requires the Swi6 transcriptional activator for viability and shows defects in cell cycle-regulated transcription. Genetics 154(4):1561-76
427) Feature_Name YMR236W TAF9 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Lethality
Citation Milgrom E, et al. (2005) TFIID and Spt-Ada-Gcn5-acetyltransferase functions probed by genome-wide synthetic genetic array analysis using a Saccharomyces cerevisiae taf9-ts allele. Genetics 171(3):959-73
428) Feature_Name YMR028W TAP42 (Essential, not in YDL homozygous screen data)
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
429) Feature_Name YPL180W TCO89
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
430) Feature_Name YGR024C THG1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
431) Feature_Name YBR240C THI2
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
432) Feature_Name YHR167W THP2
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
433) Feature_Name YHR025W THR1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
434) Feature_Name YOR297C TIM18
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
435) Feature_Name YNL273W TOF1
Experiment_Type Synthetic Growth Defect
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
436) Feature_Name YKR010C TOF2
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
437) Feature_Name YDR457W TOM1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
438) Feature_Name YJR066W TOR1
Experiment_Type Synthetic Growth Defect
Citation Chan TF, et al. (2000) A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR). Proc Natl Acad Sci U S A 97(24):13227-32
439) Feature_Name YJL164C TPK1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
440) Feature_Name YJL164C TPK1
Experiment_Type Negative Genetic
Citation Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
441) Feature_Name YDR120C TRM1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
442) Feature_Name YDR353W TRR1 (Essential, not in YDL homozygous screen data)
Experiment_Type Synthetic Rescue
Citation Machado AK, et al. (1997) Thioredoxin reductase-dependent inhibition of MCB cell cycle box activity in Saccharomyces cerevisiae. J Biol Chem 272(27):17045-54
443) Feature_Name YML028W TSA1
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
444) Feature_Name YKL033W TTI1 (Essential, not in YDL homozygous screen data)
Experiment_Type Negative Genetic
Citation Stirling PC, et al. (2011) The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components. PLoS Genet 7(4):e1002057
445) Feature_Name YLR425W TUS1
Experiment_Type Synthetic Lethality
Citation Krause SA, et al. (2012) Functional specialisation of yeast Rho1 GTP exchange factors. J Cell Sci 125(Pt 11):2721-31
446) Feature_Name YHR111W UBA4
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
447) Feature_Name YLL039C UBI4
Experiment_Type Dosage Rescue
Citation Flick K and Wittenberg C (2005) Multiple pathways for suppression of mutants affecting G1-specific transcription in Saccharomyces cerevisiae. Genetics 169(1):37-49
448) Feature_Name YBL067C UBP13
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
449) Feature_Name YBR058C UBP14
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
450) Feature_Name YER151C UBP3
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
451) Feature_Name YFR010W UBP6
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
452) Feature_Name YFR010W UBP6
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
453) Feature_Name YLR024C UBR2
Experiment_Type Positive Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
454) Feature_Name YLR024C UBR2
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
455) Feature_Name YDL170W UGA3
Experiment_Type Synthetic Growth Defect
Citation Batenchuk C, et al. (2010) Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. BMC Genomics 11():493
456) Feature_Name YOR191W ULS1
Experiment_Type Phenotypic Enhancement
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
457) Feature_Name YDR207C UME6
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
458) Feature_Name YNL229C URE2
Experiment_Type Phenotypic Enhancement
Citation Beltrao P, et al. (2009) Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol 7(6):e1000134
459) Feature_Name YNL229C URE2
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
460) Feature_Name YPL230W USV1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
461) Feature_Name YLR386W VAC14
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
462) Feature_Name YLR373C VID22
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
463) Feature_Name YGL227W VID30
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
464) Feature_Name YLR410W VIP1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
465) Feature_Name YDL185W VMA1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
466) Feature_Name YGR105W VMA21
Experiment_Type Synthetic Growth Defect
Citation Finnigan GC, et al. (2011) A Genome-Wide Enhancer Screen Implicates Sphingolipid Composition in Vacuolar ATPase Function in Saccharomyces cerevisiae. Genetics 187(3):771-83
467) Feature_Name YEL027W VMA3
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
468) Feature_Name YDR049W VMS1
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
469) Feature_Name YGR106C VOA1
Experiment_Type Synthetic Growth Defect
Citation Finnigan GC, et al. (2011) A Genome-Wide Enhancer Screen Implicates Sphingolipid Composition in Vacuolar ATPase Function in Saccharomyces cerevisiae. Genetics 187(3):771-83
470) Feature_Name YOR089C VPS21
Experiment_Type Negative Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
471) Feature_Name YHR012W VPS29
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
472) Feature_Name YDR200C VPS64
Experiment_Type Positive Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
473) Feature_Name YAL002W VPS8
Experiment_Type Positive Genetic
Citation Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10
474) Feature_Name YER072W VTC1
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
475) Feature_Name YEL002C WBP1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
476) Feature_Name YNL197C WHI3
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
477) Feature_Name YNL197C WHI3
Experiment_Type Synthetic Rescue
Citation Flick K and Wittenberg C (2005) Multiple pathways for suppression of mutants affecting G1-specific transcription in Saccharomyces cerevisiae. Genetics 169(1):37-49
478) Feature_Name YOR083W WHI5
Experiment_Type Synthetic Growth Defect
Citation Costanzo M, et al. (2004) CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast. Cell 117(7):899-913
479) Feature_Name YIL101C XBP1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
480) Feature_Name YDR369C XRS2
Experiment_Type Synthetic Lethality
Citation Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
481) Feature_Name YNL107W YAF9
Experiment_Type Synthetic Growth Defect
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
482) Feature_Name YJL141C YAK1
Experiment_Type Negative Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
483) Feature_Name YJL141C YAK1
Experiment_Type Negative Genetic
Citation Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
484) Feature_Name YML007W YAP1
Experiment_Type Positive Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
485) Feature_Name YER123W YCK3
Experiment_Type Positive Genetic
Citation Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
486) Feature_Name YDR514C YDR514C
Experiment_Type Negative Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
487) Feature_Name YKR023W YKR023W
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
488) Feature_Name YHR090C YNG2
Experiment_Type Synthetic Lethality
Citation Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74
489) Feature_Name YFR003C YPI1 (Essential, not in YDL homozygous screen data)
Experiment_Type Positive Genetic
Citation Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31
490) Feature_Name YJL056C ZAP1
Experiment_Type Negative Genetic
Citation Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420