Selected Tool: SIMILAR PHENOTYPES

The most similar phenotypes in the database

A summary of phenotypes which have the most genes in common.

Select p value for intersection

For the given 'p value' there are 32 phenotypes that pass the test


VennA Citation / Phenotype Intersection countB Citation / Phenotypep value
Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
Genes 316
208Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
Genes 340
1.722e-184
Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
Genes 340
199Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
Genes 292
1.432e-179
Citation Shuster A, et al. (2007) Alcohol-conferred hemolysis in yeast is a consequence of increased respiratory burden. FEMS Yeast Res 7(6):879-886
Phenotype MACH-Slowgrowers microbial alcohol conferred hemolysis
Genes 238
167Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
Genes 340
1.989e-149
Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
Genes 316
143Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
Genes 292
7.87e-99
Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
Genes 316
130Citation Shuster A, et al. (2007) Alcohol-conferred hemolysis in yeast is a consequence of increased respiratory burden. FEMS Yeast Res 7(6):879-886
Phenotype MACH-Slowgrowers microbial alcohol conferred hemolysis
Genes 238
9.661e-97
Citation Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36
Phenotype Sensitivity to acids Lactic Acid
Genes 128
72Citation Suzuki T, et al. (2012) Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. J Biosci Bioeng 113(4):421-30
Phenotype hypersensitivity 4.0% llactic acid (pH 2.8)
Genes 107
2.283e-95
Citation Shuster A, et al. (2007) Alcohol-conferred hemolysis in yeast is a consequence of increased respiratory burden. FEMS Yeast Res 7(6):879-886
Phenotype MACH-Slowgrowers microbial alcohol conferred hemolysis
Genes 238
125Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
Genes 292
6.008e-95
Citation Herst PM, et al. (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905
Phenotype low Plasma Membrane Electron Transport Assay for PMET
Genes 79
78Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
Genes 340
5.643e-91
Citation Ohya Y, et al. (2005) High-dimensional and large-scale phenotyping of yeast mutants. Proc Natl Acad Sci U S A 102(52):19015-20
Phenotype morphological mutant 20 or more parameters disrupted with threshold 1.00E06
Genes 156
83Citation Watanabe M, et al. (2009) Comprehensive and quantitative analysis of yeast deletion mutants defective in apical and isotropic bud growth. Curr Genet 55(4):365-80
Phenotype bud morphology: abnormal bud is abnormally elongated
Genes 173
5.027e-84
Citation Thorpe GW, et al. (2004) Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc Natl Acad Sci U S A 101(17):6564-9
Phenotype Sensitive Hydrogen Peroxide (H2O2)
Genes 116
88Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
Genes 340
3.337e-79
Citation Jorgensen P, et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297(5580):395-400
Phenotype cell size: increased mutant is among the largest 5% of haploid deletion strains
Genes 200
84Citation Ohya Y, et al. (2005) High-dimensional and large-scale phenotyping of yeast mutants. Proc Natl Acad Sci U S A 102(52):19015-20
Phenotype morphological mutant 20 or more parameters disrupted with threshold 1.00E06
Genes 156
6.046e-79
Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Hydrogen Peroxide
Genes 464
148Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
Genes 292
1.073e-76
Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
Genes 292
165Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
Genes 644
3.346e-71
Citation Perrone GG, et al. (2005) Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae. Mol Biol Cell 16(1):218-30
Phenotype respiratory growth: absent glycerol
Genes 93
75Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
Genes 340
9.492e-71
Citation Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36
Phenotype Sensitivity to acids Hydrochloric Acid
Genes 172
65Citation Suzuki T, et al. (2012) Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. J Biosci Bioeng 113(4):421-30
Phenotype hypersensitivity 4.0% llactic acid (pH 2.8)
Genes 107
8.966e-70
Citation Dilda PJ, et al. (2005) Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains. J Natl Cancer Inst 97(20):1539-47
Phenotype resistance to chemicals: decreased S-{2-[4-(dihydroxyarsino)phenylamino]-2-oxoethyl}-glutathione
Genes 87
72Citation Dilda PJ, et al. (2008) Insight into the selectivity of arsenic trioxide for acute promyelocytic leukemia cells by characterizing Saccharomyces cerevisiae deletion strains that are sensitive or resistant to the metalloid. Int J Biochem Cell Biol 40(5):1016-29
Phenotype sensitive arsenic trioxide
Genes 341
2.504e-69
Citation Teixeira MC, et al. (2009) Genome-wide identification of Saccharomyces cerevisiae genes required for maximal tolerance to ethanol. Appl Environ Microbiol 75(18):5761-72
Phenotype resistance to chemicals: decreased ethanol (8%)
Genes 233
103Citation Dias PJ, et al. (2010) Insights into the mechanisms of toxicity and tolerance to the agricultural fungicide mancozeb in yeast, as suggested by a chemogenomic approach. OMICS 14(2):211-27
Phenotype high susceptibility 1.2 or 1.5_mg/L mancozeb
Genes 286
8.239e-68
Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype mitochondrial morphology: abnormal morphology is somewhat affected; a fraction of cells exhibit wild-type mitochondrial morphology
Genes 83
66Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
Genes 292
4.505e-66
Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Menadione
Genes 249
145Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
Genes 644
2.249e-64
Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Hydrogen Peroxide
Genes 464
204Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
Genes 644
4.232e-64
Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Hydrogen Peroxide
Genes 464
142Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
Genes 340
2.632e-59
Citation Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36
Phenotype Sensitivity to acids Acetic Acid
Genes 217
75Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Ibuprofen
Genes 175
5.87e-57
Citation Thorpe GW, et al. (2004) Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc Natl Acad Sci U S A 101(17):6564-9
Phenotype Sensitive Hydrogen Peroxide (H2O2)
Genes 116
72Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
Genes 316
9.11e-57
Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
Genes 292
126Citation Yoshikawa K, et al. (2009) Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae. FEMS Yeast Res 9(1):32-44
Phenotype resistance to chemicals: decreased ethanol (8%)
Genes 445
2.486e-56
Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
Genes 340
161Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
Genes 644
8.671e-55
Citation Corbacho I, et al. (2005) A genome-wide screen for Saccharomyces cerevisiae nonessential genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccharides. Fungal Genet Biol 42(9):773-90
Phenotype genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccha low dye binding (ldb) phenotype
Genes 194
75Citation Aouida M, et al. (2004) A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to the anticancer drug bleomycin. Cancer Res 64(3):1102-9
Phenotype Sensitive to BLM Bleomycin (2.0 _g/ml)
Genes 207
1.061e-54
Citation Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36
Phenotype Sensitivity to acids Acetic Acid
Genes 217
59Citation Suzuki T, et al. (2012) Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. J Biosci Bioeng 113(4):421-30
Phenotype hypersensitivity 4.0% llactic acid (pH 2.8)
Genes 107
1.788e-52
Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
Genes 340
75Citation McLaughlin JE, et al. (2009) A genome-wide screen in Saccharomyces cerevisiae reveals a critical role for the mitochondria in the toxicity of a trichothecene mycotoxin. Proc Natl Acad Sci U S A 106(51):21883-8
Phenotype resistance to chemicals: increased trichothecene (4 uM)
Genes 133
3.014e-52
Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
Genes 316
58Citation Herst PM, et al. (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905
Phenotype low Plasma Membrane Electron Transport Assay for PMET
Genes 79
4.187e-52
Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
Genes 316
99Citation Perrone GG, et al. (2005) Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae. Mol Biol Cell 16(1):218-30
Phenotype chemical compound excretion: increased glutathione SD medium
Genes 268
3.379e-51
Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
Genes 316
150Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
Genes 644
6.337e-51
Citation Bonangelino CJ, et al. (2002) Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol Biol Cell 13(7):2486-501
Phenotype secreted strong-to-moderate levels of carboxypeptidase Y Screen for secretion of CPY into the medium
Genes 148
71Citation Perrone GG, et al. (2005) Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae. Mol Biol Cell 16(1):218-30
Phenotype chemical compound excretion: increased glutathione SD medium
Genes 268
9.553e-51